Zinc Undecylenate
Manufactured by Nova Industries
Nova Industries manufactures Zinc Undecylenate, a highly effective antifungal agent derived from natural Castor Oil.
As the zinc salt of Undecylenic Acid, this compound combines the fungistatic properties of the fatty acid with the astringent and healing properties of zinc. It is the gold standard active ingredient for topical antifungal powders and creams, widely recognized for its safety profile and superior efficacy compared to the free acid alone.
1. Technical Advantages
Zinc Undecylenate is preferred in pharmaceutical formulations due to three key biochemical advantages:
- Superior Efficacy: Research indicates that the fungicidal effect of undecylenate salts is up to four times higher than that of free Undecylenic Acid.1
- Amphiphilic Structure: The molecule possesses a unique amphiphilic structure (containing both hydrophilic and lipophilic parts). This grants it excellent skin bio-affinity, allowing it to adhere well to the skin surface and penetrate fungal cell membranes effectively.2
- Synergistic Action: It is most often formulated in combination with Undecylenic Acid (e.g., 20% Zinc Undecylenate + 2% Undecylenic Acid).3 This combination treats the infection while the zinc reduces inflammation and “weeping” associated with skin irritation.
2. Pharmaceutical Applications
Topical Antifungals (OTC & Rx)
- Tinea Pedis (Athlete’s Foot): The primary application. It effectively eradicates the fungi responsible for Athlete’s foot while relieving the associated itching, burning, and irritation.4
- Body Powders: Used in medicated talcum powders to prevent “Jock Itch” (Tinea cruris) and diaper rash. The zinc component acts as a mild astringent, helping to keep moist areas dry, which inhibits fungal growth.
Safety Profile
- Adverse Reactions: It is extremely well-tolerated.5 Clinical history shows virtually no side effects or adverse reactions in standard topical preparations (such as foot powders containing 20% Zinc salt), making it suitable for sensitive skin and long-term use.
3. Technical Specifications (TDS)
Nova Industries guarantees a pharmaceutical-grade fine powder meeting USP/BP standards.
| Parameter | Specification | Test Method |
| Product Name | Zinc Undecylenate | — |
| Synonyms | Zinc diundec-10-enoate; Undecylenic Acid Zinc Salt | — |
| CAS Number | 557-08-4 | — |
| Chemical Formula | $C_{22}H_{38}O_4Zn$ | — |
| Molecular Weight | 431.92 g/mol | — |
| Physical State | Solid (Fine Powder) | Visual |
| Appearance | White to creamy-white powder | Visual |
| Assay (Purity) | 98.0% – 102.0% | Titration |
| Zinc Content | 13.5% – 15.0% | Complexometric |
| Melting Point | 115°C – 121°C | — |
| Loss on Drying | 1.5% Max | — |
| Solubility | Insoluble in Water / Alcohol | — |
| Particle Size | 100% passing 100 Mesh | Sieve Analysis |
Packaging & Storage
- Packaging: 25 Kg Multi-wall Paper Bags with Polyliner / 25 Kg Fiber Drums.
- Storage: Store in a cool, dry place. The fine powder is hygroscopic and should be protected from moisture to prevent clumping.
For Pharmaceutical Formulations:
Nova Industries
Website: https://novaind.in/